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Normal hip xray compared to oa4/9/2024 ![]() Most investigations of muscle properties in hip OA have included individuals in advanced stages of the disease. ![]() If muscle weakness were also found to be a feature of mild-moderate hip OA, then interventions such as resistance training that target muscle weakness and prevent the development of strength asymmetries characteristic of advanced hip OA may be warranted in earlier stages of the disease. At present however, there is limited understanding of the extent and pattern of muscle weakness in earlier stages of the disease. Clinical practice guidelines recommend land-based therapeutic exercise for the management of hip OA, most notably resistance training, which can reduce pain, stiffness and self-reported disability, and improve strength, physical function and joint range of motion. Individuals with advanced hip OA exhibit generalized muscle weakness of the affected limb, which is underpinned by a combination of muscle atrophy, reduced muscle density, and muscle inhibition. ![]() Conservative non-pharmacological interventions focus primarily on alleviating pain and improving function. Hip OA has no cure, and progression to more advanced disease occurs in many patients. These deficits can limit performance of activities of daily living and diminish quality of life. People with hip osteoarthritis (OA) often experience joint pain, stiffness, reduced joint range of motion, and muscle weakness. Early interventions to target muscle weakness and prevent the development of strength asymmetries that are characteristic of advanced hip OA appear warranted. ConclusionsĪtrophic, bilateral hip and knee muscle weakness is a feature of individuals with mild-to-moderate hip OA. There were no between-limb strength differences or volume differences within either group. Participants in the hip OA group demonstrated significantly lower knee flexor, knee extensor, hip flexor, hip extensor and hip abductor strength compared to controls and had significantly lower volume of the adductor, hamstring and quadriceps groups, and gluteus maximus and gluteus minimus muscles, but not tensor fasciae latae or gluteus medius muscles. A full-factorial, two-way General Linear Model was used to assess differences between groups and between limbs. Hip and thigh muscle volumes were measured from lower limb magnetic resonance images. Isometric strength of the hip and knee flexors and extensors, and hip abductors and adductors were measured. Nineteen individuals with mild-to-moderate symptomatic and radiographic hip OA ( n = 12 unilateral n = 7 bilateral) and 23 age-matched, healthy controls without radiographic hip OA or hip pain participated. This study compared hip and knee muscle strength and volumes between individuals with mild-to-moderate symptomatic and radiographic hip OA and a healthy control group. However, the extent and pattern of muscle weakness, including any between-limb asymmetries, in early stages of the disease are unclear. Individuals with advanced hip osteoarthritis (OA) exhibit generalized muscle weakness of the affected limb and so clinical practice guidelines recommend strength training for the management of hip OA.
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